The American College of Obstetricians and Gynecologists (ACOG) makes the following recommendations for the prevention and treatment of nausea and vomiting.of pregnancy.
The following are based on consistent scientific evidence:
The following recommendations are based on limited or inconsistent scientific evidence:
- Taking a multivitamin at the time of conception may decrease the severity of symptoms.
- Taking Vitamin B6 or Vitamin B6 plus doxylamine (an antihistamine) is safe and effective and should be considered a first-line treatment.
- Ginger has shown beneficial effects and can be considered a nonpharmacologic option.
- Antihistamine H1 receptor blockers, phenothiazines, and benzamines have been shown to be safe and effective in treating refractory cases.
- Early treatment of symptoms is recommended to prevent progression to hyperemesis gravidarum.
- Treatment with methylprednisolone (a steroid) may be effective in severe cases, but should be a treatment of last resort due to its potential risk to the fetus.



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