I LOVE Curell Continuous Care ... it's AWESOME! My hands around the knuckles were so dry they were starting to crack and bleed a little, I've used it half a dozen times and its like they were never dry. Also maybe buying a liquid hand soap that has a moisturizer in it would help. I used to do this to my feet but you can do the same for hands and a pair of cotton gloves instead of socks: put vaseline/petroleum jelly on your hands then put on the gloves before bed and usually by the next day theres at least some difference.