My sister had a doctor's appointment yesterday morning, and was given Clomipramine 25mg, for OCD and anxiety. He also prescribed Metoclopramide 10mg (an anti-emetic) because she's known to react badly to anti-depressants. Anyway, she took her first dose earlier, and within the hour was complaining of nausea, dizziness and fatigue. It took two anti-emetics for the nausea to ease, and she's now napping because of the drowsiness. I know it sounds very straight-forward, but it sure isn't in my head. She has never had any side effect besides nausea from medications. The only time she naps during the day is when she's ill. I'm scared that this might actually be the start of a bug that she's picked up from the surgery. Would fatigue really come on so soon after the first dose? We share a room and I'm terrified.