Hi guys! I have been suffering from a lot of issues with my stomach for a very long time now. Thursday, the gastroenterologist put me on Zofran. I took it all day Friday, and at first I felt amazingly better. Later that day and through the night though, I had a lot of stomach cramping and become completely unable to have a BM - it was like my bowels weren't moving at all. I stopped taking it over the night and morning today to see if I could get my bowels moving again...I have, but I've also become very ill...needing to V. I went ahead and bought some stool softener/bowel stimulant pills to take with the Zofran and I went ahead and took a dose of the Zofran. I still don't feel great...but it has kicked in and helped somewhat. Can anyone give me advice or have any stories about experiences with this and other medications for N and V? Also...does anyone on here suffer from gastroparesis?