I'm not really sure what the difference between the two are... but I have taken Compazine before. My doctor originally prescribed me Zofran but since it was soooo expensive he changed it to Compazine and I think it really worked. I didn't have any bad side effects. I think I may have had fp or some kind of sv because I rememeber only going out to eat for lunch and that was the only thing I ate and I didn't feel hungry or had an appetite which during that the time was weird for me because I ate a lot and my emet wasn't bad. Anyways, I wsa getting ready for bed and I was feeling a little off and my face started tingling and I just tried to ignore it and I went to bed and my boyfriend hugged me and like squezzed my stomach and I had to run to the bathroom, but I first ran and took maybe one or two compazines and felt pretty n* and had terrible d* for a while, I swear I thought it was going to happen, I like felt it in my stomach and it felt just like when I v* a few years before and it didn't happen. I think the Compazine really did work.