Pepto works the best for d*, but I've taken it for acid reflux too. I mostly take Zantac/Ranitidine when I have acid like Asil said. Zantac is the exact same thing as Ranitidine. Ranitidine is just the generic version, Zantac is a name brand - you can get either in various strengths. I take 150mg twice per day when my acid is really bad.