Yes, 2 times both from severe menstrual cramps. The first time I was at work. The second time I was nauseated and I knew it was about to happen. Before I could get up and go to the bathroom, I fainted and the scary part is I v* while i was out. Thankfully I was sitting up and didn't aspirate. It was so gross and frightening. I am happy to say I have gone thru menopause and I don't have those awful cramps anymore!!